Association of HDL-C Levels with Stroke and All-cause Mortality: A Prospective Cohort Study from the CHARLS - PubMed
3 days ago
- #Mortality
- #Stroke
- #HDL-C
- Study explores the relationship between HDL-C levels and stroke/all-cause mortality in middle-aged and elderly Chinese populations.
- HDL-C was found to be a protective factor against stroke, especially in males, normal BMI groups, non-dyslipidemia groups, and hypertensive groups.
- No significant association was observed between HDL-C and all-cause mortality after adjusting for confounders.
- BMI was identified as a mediator, accounting for 25% of HDL-C's effect on stroke risk.
- The study utilized various statistical methods including Cox regression, Kaplan-Meier curves, and restricted cubic spline regression for robust analysis.
- Findings highlight the importance of HDL-C in stroke risk assessment but not in all-cause mortality.