Performance of cardiovascular disease risk prediction tools in chronic obstructive pulmonary disease - PubMed
4 hours ago
- #Cardiovascular Disease Risk
- #Chronic Obstructive Pulmonary Disease
- #Risk Prediction Tools
- QRISK3 underestimates CVD risk in COPD, raising concerns about similar tools.
- PREVENT shows the highest discrimination (0.76), while Pooled and Framingham scores lower (0.66 and 0.57).
- PREVENT underestimates risk (O/E 1.25), while Pooled and Framingham overestimate by about 30%.
- Discrepancies vary by age and sex, with PREVENT underestimating more in younger adults and Pooled overestimating in older adults.
- All three models retain clinical utility across risk thresholds and could improve with further calibration.