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Reversible cerebral vasoconstriction syndrome: A narrative review - PubMed

3 hours ago
  • #neuroimaging
  • #thunderclap headache
  • #cerebrovascular disorders
  • RCVS is characterized by recurrent thunderclap headaches and transient segmental vasoconstriction of cerebral arteries, typically resolving within 3 months.
  • Triggers include vasoactive substances, pregnancy, postpartum state, and physical or emotional stress.
  • Complications can include subarachnoid hemorrhage, ischemic stroke, and cerebral edema.
  • Differentiating RCVS from conditions like primary angiitis of the CNS, aneurysmal SAH, and cerebral venous thrombosis is crucial due to overlapping features but differing treatments.
  • Advances in neuroimaging, such as MRA and vessel wall imaging, have improved diagnostic accuracy.
  • Management focuses on eliminating triggers and symptomatic support; calcium channel blockers are commonly used, though their impact on disease evolution is uncertain.
  • Many patients recover without major sequelae, but chronic symptoms like long-term headaches and cognitive impairment suggest a post-RCVS syndrome, requiring ongoing follow-up.