Polysaccharide from Ribes nigrum L. Ameliorates Diabetic Kidney Injury in Mice by Modulating the GUDCA/GPBAR1 Axis through the Remodeling of the Gut Microbiota - PubMed
4 hours ago
- #Gut Microbiota
- #Diabetic Nephropathy
- #Polysaccharides
- Polysaccharide from Ribes nigrum L. (BCP) improves diabetic kidney injury in mice.
- BCP modulates the GUDCA/GPBAR1 axis by remodeling gut microbiota.
- BCP enriches Akkermansia muciniphila in the gut, which correlates with increased GUDCA levels.
- GUDCA activates GPBAR1, reducing kidney inflammation and fibrosis.
- BCP shows potential as a dietary strategy for diabetic nephropathy.