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Bidirectional brain-heart interactions in health and disease - PubMed

5 hours ago
  • #Brain-Heart Interaction
  • #Neurocardiology
  • #Clinical Implications
  • The brain and heart maintain continuous bidirectional communication that is crucial for adapting to environmental changes.
  • Disruptions in brain-heart interactions can lead to organ dysfunction, such as cardiac issues from psychological stress or brain injury, and cognitive disorders from heart disease.
  • Clinical implications include Takotsubo syndrome from emotional stress or brain disorders, stroke-heart syndrome, and cognitive dysfunction in heart failure or atrial fibrillation.
  • Neuronal and humoral mediators facilitate brain-heart interactions, with advanced methods now available to study these relationships.
  • Sex and gender differences exist in the bidirectional brain-heart relationship, affecting disease manifestation and outcomes.
  • The review emphasizes the importance of understanding these interactions to address health issues in both neurological and cardiovascular contexts.