Real-world Adherence to European Association of Urology-recommended Non-muscle-invasive Bladder Cancer Management: From Evidence-based Practice to Oncological Outcomes - PubMed
a day ago
- #Guideline Adherence
- #Bladder Cancer
- #Oncological Outcomes
- Adherence to EAU guidelines for NMIBC management is crucial for optimal outcomes.
- Study analyzed 2194 NMIBC patients across six European centers (2014-2021).
- Adherence rates were low: EI (22%), re-TURBT (44%), intravesical instillations (29%).
- Adherence to guidelines significantly improved RFS and PFS.
- EI adherence improved RFS (79% vs 61%; HR 0.60).
- Re-TURBT adherence improved RFS (70% vs 54%; HR 0.53) and PFS (94% vs 87%; HR 0.41).
- Intravesical instillations adherence improved RFS (72% vs 53%; HR 0.49) and PFS (95% vs 89%; HR 0.47).
- Nonadherence reasons were not reported in the study.
- Improving guideline-based care delivery should be a priority in NMIBC management.