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High-fat diet leads to male reproductive dysfunction by disrupting lipid-droplet-mediated organelle crosstalk - PubMed

5 days ago
  • #Reproductive dysfunction
  • #Lipid droplets
  • #High-fat diet
  • High-fat diet causes male reproductive dysfunction by disrupting organelle crosstalk mediated by lipid droplets.
  • The study highlights the role of lipid droplets in affecting mitochondria-endoplasmic reticulum contacts and testosterone production.
  • Animal experiments were approved by Top Biotech Co., Ltd, following ICLAS guidelines.
  • The authors declare no competing interests.
  • References discuss the impact of Western diets, trans fats, and obesity on chronic diseases like cardiovascular disease, diabetes, and non-alcoholic fatty liver disease (NAFLD).