Brainwide blood volume reflects opposing neural populations - PubMed
4 hours ago
- #brain blood volume
- #hemodynamic responses
- #neural populations
- Brainwide blood volume fluctuations are consistent across brain states and regions but differ between two opposing neural populations.
- Functional ultrasound imaging (fUSI) shows whisking, a marker of arousal, is linked to brainwide changes in blood volume.
- Neurons that increase activity with whisking have distinct hemodynamic response functions compared to those that decrease activity.
- The summed contributions of these opposing populations predict blood volume across different brain states.
- Brainwide recordings reveal these opposing neural populations exist throughout the entire brain, explaining regional differences in blood volume fluctuations.