Association of Multiple Plasma Metals With Cerebral Microbleeds: A Brain Magnetic Resonance Imaging-Based Study - PubMed
4 hours ago
- #plasma metals
- #cerebral microbleeds
- #MRI study
- Study investigates the association between plasma metals and cerebral microbleeds (CMBs).
- Data from the META-KLS study involving 1206 adults (median age 54.4 years, 52.2% female) was analyzed.
- 291 participants (24.1%) were identified as CMBs cases via brain MRI.
- Plasma concentrations of 14 metals were measured, with calcium, magnesium, lead, and vanadium showing higher CMBs risk.
- Odds ratios (ORs) for CMBs risk: 1.36 for calcium, 1.34 for magnesium, 1.38 for lead, and 1.25 for vanadium.
- Multi-metal analysis highlighted lead (28.6%), magnesium (8.0%), and calcium (3.6%) as significant contributors.
- Limiting exposure and monitoring these metals may help prevent CMBs.