Associations of intrinsic capacity and social isolation with cardiometabolic diseases: A prospective multi-cohort study - PubMed
3 hours ago
- #social isolation
- #intrinsic capacity
- #cardiometabolic diseases
- The study found that impaired intrinsic capacity (IC) is associated with an increased risk of cardiometabolic diseases (CMD).
- Social isolation modifies the association, with the joint effect of impaired IC and social isolation leading to a higher risk, particularly for diabetes.
- The relationship was most significant for stroke across different cohorts, with pooled hazard ratios indicating a strong association.
- The study used data from three aging cohorts (CHARLS, ELSA, KLoSA) and included 12,792 participants followed for a median of 7 years.
- Results varied by country and CMD subtype, highlighting the need for tailored public health interventions.