The burden of cancers and their variations across the states of US the global burden of disease study 1990-2021 - PubMed
a day ago
- #risk factors
- #geographic disparities
- #cancer burden
- The study analyzed cancer incidence, deaths, and disability-adjusted life years (DALYs) across U.S. states from 1990 to 2021 using GBD 2021 data.
- In 2021, the U.S. reported 16.2 million new cancer cases, 715,189 deaths, and 16 million DALYs, with significant regional disparities.
- A 'cancer belt' in the southern U.S. showed mortality and DALY rates over 20% higher than the national average.
- Gender disparities were noted: females had higher incidence rates, while males had higher mortality and DALY rates, though both improved over time.
- Leading cancers varied by gender: prostate in males (highest incidence), breast in females (highest incidence), and lung cancer in both (highest mortality and DALYs).
- Top risk factors for cancer DALYs included tobacco (20.87%), dietary risks (6.81%), and high BMI (6.72%).
- Projections suggest reductions in mortality and DALYs by 2036, but gender disparities will persist, emphasizing the need for targeted interventions.
- The study highlights geographic, gender, and socioeconomic disparities, urging focus on top cancers (e.g., lung, colorectal, breast) and shared risk factors for effective policy.