Periprosthetic Joint Infection Following Total Knee Arthroplasty Is Associated with a Significantly Elevated Risk of Mortality: A Population-Level Database Study - PubMed
4 hours ago
- #Total knee arthroplasty
- #Periprosthetic joint infection
- #Mortality risk
- Periprosthetic joint infection (PJI) is the most common reason for revision total knee arthroplasty (TKA).
- Patients who develop PJI within 1 year after TKA have a significantly higher 10-year mortality rate compared to those without PJI (7.2% vs. 1.6%).
- Risk factors for PJI include being male, frailty, higher Charlson-Deyo score, congestive heart failure, and chronic obstructive pulmonary disease.
- The study used a large population-level database with 263,204 primary TKA patients, of which 1,228 (0.5%) developed PJI within 1 year.
- The increased mortality risk associated with PJI warrants further investigation into prevention, diagnosis, and management strategies.