ASH ISTH 2026 guidelines for Anticoagulant Prophylaxis of Pediatric Patients at Risk of Venous Thromboembolism - PubMed
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- #clinical guidelines
- #pediatrics
- #thromboprophylaxis
- The guidelines provide 12 recommendations for anticoagulant prophylaxis in pediatric patients at risk of venous thromboembolism (VTE).
- For pediatric patients with solid cancer, trauma, or critical illness, conditional recommendations suggest no anticoagulant prophylaxis.
- For pediatric patients with antiphospholipid antibody syndrome or on long-term total parenteral nutrition, conditional recommendations suggest using anticoagulant prophylaxis.
- Other subgroups addressed include those with acute lymphoblastic leukemia or lymphoma, surgical/hospitalized patients, and those with central venous access devices.
- High-quality data on pediatric VTE prophylaxis are scarce, and key research priorities include developing subgroup-specific VTE risk assessment models and evaluating risk-stratified strategies.