Significant kidney impairment in pediatric inflammatory bowel disease and practice points for pediatric gastroenterologists - PubMed
a day ago
- #chronic kidney disease
- #kidney impairment
- #pediatric IBD
- Children with inflammatory bowel disease (IBD) have an increased risk of kidney disorders, including significant kidney impairment (SKI) and chronic kidney disease (CKD).
- A study collected 42 cases of SKI in children with IBD from the PIBD-SETQuality Safety Registry, with tubulo-interstitial nephritis (TIN) being the most common diagnosis (15 cases).
- 16 cases were confirmed via renal biopsy, with 10 being TIN. 12 patients developed CKD.
- IBD medication was frequently reported as a cause of SKI (15 cases), but there was low agreement among experts on the exact etiology.
- The study provides recommendations for screening, follow-up, and referral for children with IBD and SKI, emphasizing the challenges in confirming the etiology of SKI.