Association between estimated glucose disposal rate and cause-specific mortality among individuals with metabolic dysfunction-associated steatotic liver disease - PubMed
9 hours ago
- #mortality
- #eGDR
- #MASLD
- Study examines the association between estimated glucose disposal rate (eGDR) and cause-specific mortality in patients with metabolic dysfunction-associated steatotic liver disease (MASLD).
- 6,847 MASLD patients from NHANES 1999-2018 were divided into eGDR quartiles and followed for a median of 8.8 years.
- Higher eGDR levels were significantly associated with lower risks of all-cause, cardiovascular, and diabetes mortality.
- ROC analyses showed modest predictive performance of eGDR for mortality outcomes, with the highest AUC for diabetes mortality (0.729).
- Subgroup analyses confirmed the robustness of the association between eGDR and mortality risks.
- Findings highlight the prognostic relevance of insulin resistance in MASLD patients and support eGDR's role in cardiometabolic risk stratification.