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Association of residential green space, blue space, and natural environment with the incident heart failure and cardiac morpho-functional phenotypes: a UK biobank-based prospective cohort and imaging

4 hours ago
  • #Heart Failure
  • #Cardiac MRI
  • #Green Space
  • Higher residential green space, blue space, and natural environment exposure is associated with lower heart failure (HF) incidence.
  • The study analyzed 437,429 UK Biobank participants over a median follow-up of 13.9 years, identifying 16,564 incident HF cases.
  • Green space exposure within 1000-m buffers showed the most robust cardioprotective effects, reducing HF risk by 13% (HR 0.87).
  • Blue space exposure within 1000-m buffers reduced HF risk by 23% (HR 0.77).
  • Natural environment exposure within 1000-m buffers reduced HF risk by 15% (HR 0.85).
  • Cardiac MRI data revealed that higher green space exposure correlated with reduced odds of adverse cardiac remodelling patterns.
  • The study adjusted for sociodemographic, lifestyle, clinical, genetic, and air pollution factors, ensuring robust conclusions.
  • This is the first study to link natural environments to favourable cardiac morpho-functional phenotypes using CMR imaging.