Exercise timing and circadian regulation of metabolism in type 2 diabetes - PubMed
3 hours ago
- #circadian rhythm
- #exercise timing
- #type 2 diabetes
- The circadian system regulates daily metabolic and hormonal rhythms, but in type 2 diabetes, disrupted clock gene oscillations impair metabolic regulation.
- Insulin resistance, mitochondrial dysfunction, and chronic inflammation contribute to circadian misalignment in type 2 diabetes.
- Exercise can restore circadian rhythms, with afternoon and evening exercise showing greater benefits for glycemic control and insulin sensitivity compared to morning exercise.
- Exercise intensity may influence the metabolic benefits of timed exercise in individuals with type 2 diabetes.
- Further research is needed to understand the mechanisms behind exercise timing effects and to develop clinical recommendations.