Systematic review: Safety and efficacy of atomoxetine in children and adolescents with autism spectrum disorder - PubMed
7 hours ago
- #atomoxetine
- #ADHD
- #autism spectrum disorder
- Systematic review assesses Atomoxetine's efficacy and safety for ADHD symptoms in children and adolescents with autism spectrum disorder (ASD).
- Included studies: 16 clinical trials (2 RCTs, 4 open-label trials, 8 extension studies, 1 observational study, 1 crossover study).
- Atomoxetine was found to be well-tolerated and safe, with response rates similar to methylphenidate but with fewer adverse effects.
- Limited high-power studies available; more trials needed for conclusive recommendations.
- Atomoxetine could be a safe off-label option for managing ADHD symptoms in ASD due to its favorable tolerability profile.