Unveiling a macrophage-driven inflammatory dysregulation: NF-κB-mediated hyperinflammation links 6PPD-Q exposure to viral immunopathology - PubMed
5 days ago
- #NF-κB
- #6PPD-Q
- #Macrophage
- 6PPD-Q exposure increases host susceptibility to viral pneumonia.
- The study links 6PPD-Q to NF-κB-mediated hyperinflammation in macrophages.
- Mice exposed to 6PPD-Q showed higher mortality and severe pulmonary pathology during viral infections.
- Macrophage depletion reversed the adverse effects of 6PPD-Q exposure.
- Findings highlight the importance of environmental health management in preventing respiratory diseases.