Intermittent fasting inhibits ferroptosis by modulating CD36 and its palmitoylation to alleviate diabetic dry eye - PubMed
3 hours ago
- #Ferroptosis
- #Intermittent fasting
- #Diabetic dry eye
- Intermittent fasting helps alleviate diabetic dry eye by inhibiting ferroptosis through modulation of CD36 and its palmitoylation.
- The study was conducted with approval from the Ethics Committee of Zhongshan Ophthalmic Center, ensuring compliance with international animal experimentation guidelines.
- Key findings suggest a connection between hyperglycemia and ocular surface damage, leading to dry eye in diabetic conditions.
- The research highlights the role of mitochondrial bioenergetic deficits in the lacrimal gland as a contributing factor to diabetic dry eye.
- Funding for the study was provided by various sources including the Guangzhou Municipal Science and Technology Project and the National Natural Science Foundation of China.