GLP-1 and dual GIP/GLP-1 agonists in obese patients with HFpEF: a systematic review and meta-analysis of RCTs - PubMed
3 hours ago
- #GLP-1 agonists
- #meta-analysis
- #HFpEF
- Systematic review and meta-analysis examined GLP-1 and dual GIP/GLP-1 agonists in obese patients with HFpEF (heart failure with preserved ejection fraction).
- Focus on efficacy, noting that these agonists may improve outcomes in heart failure with mildly reduced or preserved ejection fraction.
- Involves assessment of risk of bias using RoB 2 tool, following PRISMA 2020 guidelines for reporting.
- Studies include references to semaglutide and tirzepatide as examples of agonists used.
- Authors declared no competing interests, with ethics approval not required due to use of published data.