Current evidence and knowledge gaps in family planning and pregnancy in myasthenia gravis, NMOSD, and MOGAD - PubMed
a day ago
- #pregnancy
- #neuroimmunology
- #autoimmune-diseases
- Myasthenia gravis, NMOSD, and MOGAD are antibody-mediated neuroimmune disorders affecting women in reproductive years.
- Disease exacerbations (myasthenia gravis) and attacks (NMOSD, MOGAD) can occur during pregnancy and postpartum, leading to long-term maternal disability.
- Current drug labels often recommend conservative approaches, unnecessary washouts, or avoidance of breastfeeding, creating uncertainty.
- Preliminary data suggest selected newer therapies could be continued during pregnancy to maintain disease stability and are compatible with breastfeeding.
- Expert recommendations are provided for therapy choice, infant vaccinations, and fetal/infant monitoring in these conditions.
- Conflict of interest statements detail funding and consulting relationships of the authors with various pharmaceutical companies.