A phosphorylation-dependent ubiquitination switch orchestrates nuclear immune reprogramming upon chitin perception - PubMed
9 hours ago
- #plant immunity
- #phosphorylation
- #ubiquitination
- 14-3-3 proteins, OsGF14f and OsGF14c, enhance rice resistance against Magnaporthe oryzae.
- E3 ligase OsPUB20 targets OsGF14f and OsGF14c for degradation, negatively regulating immunity.
- Chitin perception activates OsRLCK185, which phosphorylates OsPUB20, stabilizing OsGF14f and boosting resistance.
- During infection, OsGF14f moves to the nucleus, degrading OsWRKY42 to promote defense responses.
- The study reveals a phosphorylation-dependent ubiquitination switch linking chitin perception to nuclear immune reprogramming.