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Association between cumulative exposure to metabolic score for visceral fat and the risk of stroke in a population with cardiovascular-kidney-metabolic syndrome stages 0-3: a nationwide prospective co

5 hours ago
  • #CKM syndrome
  • #visceral fat
  • #stroke risk
  • The study investigates the association between cumulative metabolic score for visceral fat (METS-VF) and stroke risk in individuals with cardiovascular-kidney-metabolic (CKM) syndrome stages 0-3.
  • Data from the China Health and Retirement Longitudinal Study (CHARLS) was used, with 3,227 participants followed over five years, during which 235 experienced a stroke.
  • Higher cumulative METS-VF levels were significantly associated with increased stroke risk, with hazard ratios (HRs) rising progressively from Q2 to Q4 compared to Q1.
  • A cumulative METS-VF level above 6.53 was linked to a notably higher stroke risk (HR = 1.781, 95% CI: 1.296-2.448).
  • The findings suggest that long-term METS-VF assessment could help identify high-risk individuals for early stroke prevention in CKM syndrome stages 0-3.