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Candida pelliculosa cluster endophthalmitis: clinical profile and surgical outcomes in twelve eyes - PubMed

4 hours ago
  • #Cataract surgery complications
  • #Candida pelliculosa
  • #Endophthalmitis
  • Study describes clinical features and surgical outcomes of Candida pelliculosa cluster endophthalmitis post-cataract surgery.
  • Twelve eyes of ten patients developed endophthalmitis after uncomplicated phacoemulsification with IOL implantation.
  • All patients underwent core vitrectomy, IOL explantation, and intravitreal injections of vancomycin, ceftazidime, and voriconazole.
  • Candida pelliculosa was isolated from all explanted IOL-bag complexes; vitreous cultures were negative.
  • Mean interval from cataract surgery to presentation was 28 days with symptoms like pain, redness, and mild vision loss.
  • Mean presenting BCVA was 20/40 (0.3 LogMAR).
  • Post-vitrectomy BCVA was 20/60 (0.48 LogMAR).
  • Complications included cystoid macular edema (5 eyes), sub-Tenon triamcinolone (1 eye), and epiretinal membranes (4 eyes).
  • Seven eyes underwent secondary scleral-fixated IOL implantation after a mean of 5.2 months, achieving final BCVA of 20/32.
  • Early vitrectomy with IOL-bag explantation is crucial for infection control and favorable visual recovery.