Tissue characterization in cardiac amyloidosis: a joint consensus document by the gruppo di studio di cardiopatologia (SIAPEC) and the SIC/ANMCO Italian cardiac amyloidosis network (RIAC) - PubMed
4 days ago
- #amyloid typing
- #tissue characterization
- #cardiac amyloidosis
- Cardiac amyloidosis (CA) is caused by abnormal protein fibril accumulation in the myocardium.
- Targeted therapies for light-chain amyloidosis (AL) and transthyretin amyloidosis (ATTR) require prompt diagnosis and accurate protein typing.
- Diagnostic confirmation often requires biopsy, especially for AL and rare CA variants.
- Amyloid typing techniques include immunohistochemistry, immunofluorescence, immune electron microscopy, and mass spectrometry.
- The document provides guidance on tissue analysis and amyloid typing for clinical practice.