2025 International Consensus Meeting on Musculoskeletal Infection: Summary From Biofilm Workgroup on Treatment of Biofilm-Related Infection and Preclinical Models - PubMed
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- Musculoskeletal infections (MSKI) remain severe complications post-orthopedic surgery, burdening patients and healthcare systems globally.
- The 2025 International Consensus Meeting (ICM) included a Biofilm Section to advance basic science and translational research in MSKI.
- A 2-year Delphi process led to an in-person meeting in Istanbul, Turkey, where 47 delegates voted on 30 questions.
- Three workgroups were formed: Biofilm Basic Science, Biofilm Treatment, and Research Priorities, to interpret results and disseminate findings.
- The Biofilm Treatment Workgroup aims to guide future preclinical research, focusing on scientific rigor, therapeutic concepts, and novel drug-delivery systems.
- A critical shift in funding was noted, with a call for increased investment from industry and philanthropic partners to develop effective treatments.