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Stress-induced hyperglycemia ratio and gestational diabetes mellitus: a cross-sectional study based on NHANES database - PubMed

4 hours ago
  • #gestational diabetes
  • #NHANES study
  • #stress hyperglycemia
  • The study examined the association between Stress-induced hyperglycemia ratio (SHR) and gestational diabetes mellitus (GDM) using NHANES data from 1999 to 2016.
  • Included 461 pregnant women, with SHR identified as a significant risk factor for GDM (OR: 1.77, 95% CI: 1.37-2.28, p < 0.001).
  • Higher SHR values correlated with increased GDM risk, consistent across SHR tertiles and subgroups like education level and alcohol consumption.
  • A nonlinear relationship was found, with a threshold effect: SHR positively associated with GDM when ≤15.75, but not beyond.
  • Stratified analysis showed a significant positive correlation between SHR and GDM in early pregnancy (1-5 months; OR = 2.16, 95% CI: 1.12-4.16), but no significant association in later pregnancy (6-10 months).
  • SHR may serve as a clinical marker for early identification and intervention in GDM risk, highlighting its utility in early pregnancy.