Sexual dysfunction associated with selective serotonin reuptake inhibitors in adults with depression: a systematic review and meta-analysis - PubMed
9 hours ago
- #sexual dysfunction
- #SSRIs
- #depression
- SSRIs significantly increase the risk of orgasmic dysfunction in adults with depression.
- SSRIs are associated with reduced sexual satisfaction but show a non-significant trend toward decreased sexual desire.
- No significant differences were found in total CSFQ scores between SSRIs and placebo.
- The GRADE assessment indicated high to moderate certainty of evidence for these findings.
- The systematic review and meta-analysis included 13 RCTs, with 6 contributing to the meta-analyses.