Association Between Three Systemic Inflammatory Biomarkers and Diabetic Foot Ulcer: A Cross-Sectional Study and a Clinical Retrospective Study - PubMed
4 hours ago
- #Biomarkers
- #Diabetic Foot Ulcer
- #Systemic Inflammation
- Study investigates the association between systemic inflammatory biomarkers (SIRI, SII, AISI) and diabetic foot ulcer (DFU).
- Combines cross-sectional NHANES data analysis with a clinical retrospective study involving 34 DFU patients and 68 diabetic controls.
- Finds positive associations between elevated levels of ln SIRI, ln SII, ln AISI and increased DFU prevalence in both unadjusted and adjusted models.
- Subgroup analyses confirm stable associations across demographic and clinical subgroups.
- ROC analysis indicates SII is more reliable than SIRI and AISI for predicting DFU.
- Concludes that SIRI, SII, and AISI may serve as valuable tools for DFU risk assessment.