International guidelines on the diagnosis and treatment of NUT carcinoma - PubMed
3 hours ago
- #NUT carcinoma
- #cancer guidelines
- #BET inhibitors
- NUT carcinoma (NC) is a rare and aggressive cancer characterized by NUTM1 gene fusions, primarily BRD4-NUTM1.
- Diagnosis and treatment of NC remain challenging, with no standard treatment protocol currently available.
- Treatment options include surgical resection, radiotherapy, chemotherapy, targeted therapy, and immunotherapy.
- Future research focuses on improving diagnostics, exploring new therapies like selective BET inhibitors, and conducting basket trials for NUTM1 gene fusions.
- Multidisciplinary team collaboration is emphasized for effective NC treatment.