An expanded reference catalog of translated open reading frames for biomedical research - PubMed
3 hours ago
- #open reading frames
- #biomedical research
- #genome annotation
- An expanded reference catalog of translated open reading frames (ncORFs) for biomedical research has been developed.
- The catalog includes 28,359 ncORFs, nearly four times the size of the previous version.
- A subset of 10,127 ncORFs, termed the 'primary set', shows translation evidence comparable to canonical protein-coding genes.
- The catalog aims to make ncORFs accessible and actionable for broader research, with continuous updates planned.
- The initiative is part of the TransCODE consortium and is openly distributed via Ensembl-GENCODE.