Post-finasteride syndrome: survey of dermatologists from the Spanish Hair and Nail Disorders Group - PubMed
4 hours ago
- #Post-finasteride syndrome
- #5-alpha-reductase inhibitors
- #Dermatology survey
- Post-finasteride syndrome (PFS) involves persistent symptoms after stopping 5-alpha-reductase inhibitors (5-ARIs).
- A survey of 54 dermatologists from the Spanish Hair and Nail Disorders Group explored perceptions of PFS.
- 83.3% of respondents had never encountered PFS cases in their practice.
- 98.1% believed PFS has a psychiatric origin, and 92.6% thought 5-ARI effects are reversible after discontinuation.
- Sexual dysfunction was considered possibly related to 5-ARIs, while cognitive impairment, anxiety, and depression were seen as unrelated by most.
- Consensus was reached on 13 of 15 items, with 90.7% agreeing scientific evidence on PFS is poor.
- 85.1% identified a specific patient profile: young men with pre-existing anxiety or depression.
- Dermatologists view PFS as rare and primarily psychiatric, calling for more high-quality studies for diagnosis and management guidelines.