Association between serum α-Klotho levels and severity of periodontitis in a representative U.S. population - PubMed

3 hours ago

Study evaluates the relationship between serum α-Klotho levels and periodontitis severity in a U.S. population.
No significant association found between α-Klotho levels and periodontitis stage or grade after adjusting for confounders.
Age, smoking, and comorbidities were significant predictors of periodontitis severity.
Weak negative correlation between α-Klotho and tooth loss was not significant after adjustment.
Findings suggest α-Klotho may not be a useful biomarker for periodontitis severity.
Future longitudinal and mechanistic studies are recommended to explore α-Klotho's role further.

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