Frequency and characteristics of axial involvement in psoriatic arthritis: results from the International Multicentre AXIS Study - PubMed

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Axial involvement in psoriatic arthritis (PsA) was studied in the AXIS cohort, a prospective cross-sectional study across 19 countries.
After central imaging review, axial involvement was identified in 27.4% of 409 PsA participants, down from 37.4% in initial assessments.
Key associated features of axial involvement included younger age, male predominance, HLA-B*27 positivity, inflammatory back pain, and elevated CRP.
Imaging changes (active inflammation or structural lesions) in sacroiliac joints or spine were highly discriminative for axial involvement.

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