Short-Term Exposure to Air Pollution Increases Mortality From Hypertension and its Multiorgan Complications: A Case Crossover Study of 2.1 Million Deaths in China - PubMed
4 hours ago
- #mortality
- #air pollution
- #hypertension
- Short-term exposure to air pollution increases mortality risk in hypertensive patients, with risks varying by disease progression stage.
- The study analyzed over 2.1 million hypertension-related deaths in China (2013-2019), linking them to air pollution data (PM2.5, PM10, NO2, O3).
- Mortality risk increased stepwise with disease severity: from 1.39% for uncomplicated hypertension to 5.01% for hypertensive heart and kidney disease with cardiorenal failure.
- NO2 showed the strongest associations among the pollutants studied, with linear exposure-response relationships and no apparent threshold.
- Vulnerable groups included females, those aged ≥65, northern residents, lower educational attainment, no spousal support, and cold season exposure.
- The findings suggest a need for targeted risk stratification, especially for patients with concurrent cardiorenal failure, for environmental health advisories and clinical management.