Short-term effects of size-fractioned particulate matter on blood pressure in patients with COPD: the key role of inflammatory phenotypes - PubMed
4 hours ago
- #Particulate Matter
- #COPD
- #Blood Pressure
- Study examines short-term effects of size-fractioned particulate matter (PM) on blood pressure in COPD patients.
- Hypertension is present in about half of COPD patients, worsening prognosis.
- 82 COPD patients (42 with hypertension) participated in 281 clinical visits.
- Personal exposure to PM10, PM2.5, and ultrafine particles (UFPs) was estimated.
- UFPs and PM2.5 significantly increased systolic blood pressure (SBP), with UFPs showing earlier effects.
- Hypertensive individuals had stronger blood pressure responses to UFPs and PM2.5.
- Eosinophilic inflammatory phenotype patients were more susceptible to PM-related blood pressure increases.
- No significant effect modification was found based on smoking status.