An intralayer microcircuit in the temporal association cortex underlies sensory-induced escape in mice - PubMed
3 hours ago
- #sensory-motor integration
- #escape behavior
- #neuroscience
- The study identifies the temporal association cortex (TeA) as a critical hub for sensory-induced escape behavior in mice.
- Three distinct neuron subtypes within TeA layer 5 (L5) CaMKII neurons were characterized: sensory-motor decision neurons (IT), motor command neurons (PT), and sensory neurons.
- A laminar IT-PT microcircuit converts sensory input into decisions and commands for escape locomotion.
- The research utilized in vivo electrophysiology, optogenetics, and chemogenetics to analyze neural circuits.
- Findings contribute to understanding how neural circuits translate sensory input into adaptive behaviors.