Challenges and future directions for Mendelian randomization - PubMed
2 hours ago
- #Mendelian Randomization
- #Genetic Epidemiology
- #Causal Inference
- Mendelian randomization has transitioned from a niche method to a widely used approach in research.
- Current studies often fail to fully utilize available data and techniques to test assumptions empirically.
- Future progress requires integrating evidence from molecular, cellular, animal, and quasi-experimental studies.
- The changing landscape of genetic and genomic data offers both new challenges and opportunities for the framework.