Evaluation of clinical responses to probiotics and colchicine in PFAPA patients based on autoinflammatory diseases activity index (AIDAI) scores - PubMed
9 hours ago
- #probiotics
- #PFAPA syndrome
- #colchicine
- Study evaluates clinical responses to probiotics and colchicine in PFAPA patients using AIDAI scores.
- 130 PFAPA patients included (97 on colchicine, 33 on probiotics).
- Both groups showed significant early clinical response with decreased AIDAI scores (p < 0.001).
- Colchicine group had longer time to first attack compared to probiotics (p = 0.048).
- Short-term improvement in PFAPA activity similar for both treatments.
- Differences in time to first attack and adverse effects noted for treatment selection.
- Study supports probiotic use and personalized treatment approaches in PFAPA.