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Medication Adherence in Hypertension: A Cluster Randomized Clinical Trial - PubMed

3 hours ago
  • #medication adherence
  • #hypertension
  • #clinical trial
  • The TEAMLET trial tested a multicomponent intervention to improve medication adherence in patients with uncontrolled hypertension, using linked electronic health record-pharmacy data and team-based care.
  • The intervention included automated identification of nonadherence, screening for barriers by medical assistants, alerts to clinicians, and adherence discussions, but showed no significant improvement in adherence or blood pressure compared to usual care.
  • Results from 1726 patients indicated no difference in the change in proportion of days covered (PDC) from baseline to 12 months between intervention and control groups, with both showing similar increases.
  • The study concluded that the intervention did not lead to improvements, highlighting the challenge of addressing medication nonadherence in hypertension management despite technological and team-based approaches.