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Strategies to target PD-1/PD-L1 in the tumor microenvironment - PubMed

2 hours ago
  • #immunotherapy
  • #PD-1/PD-L1
  • #tumor microenvironment
  • Cancer immunotherapy is a key method in cancer treatment by activating the immune system.
  • The PD-1/PD-L1 pathway in the tumor microenvironment promotes tumor immune escape by impairing T cell responses.
  • Blocking PD-1/PD-L1 enhances antitumor immune response and improves therapeutic outcomes.
  • Anti-PD-1/PD-L1 antibodies have shown significant antitumor effects in clinical practice.
  • New strategies targeting PD-1/PD-L1 regulatory mechanisms can reverse tumor immunosuppressive microenvironment.
  • Recent studies highlight the fine regulation of the PD-1/PD-L1 pathway in the tumor microenvironment.