Detecting phosphorylated MLKL in murine tissues - PubMed
3 hours ago
- #Necroptosis biomarker
- #Murine tissue analysis
- #MLKL phosphorylation
- Necroptosis is initiated by RIPK3 phosphorylation of MLKL.
- Phosphorylated MLKL oligomers perforate cellular membranes, leading to cell death.
- MLKL phosphorylation is a key biomarker for necroptosis detection.
- The method detects phosphorylated MLKL in influenza-infected lung tissues and tumors treated with CBL0137.
- CBL0137, Influenza A virus, MLKL, Necroptosis, RIPK3, Z-DNA, Z-RNA, and ZBP1 are key terms.