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Underweight and the Risk of Atrial Fibrillation in the Asian Population - PubMed

3 hours ago
  • #underweight
  • #atrial-fibrillation
  • #Asian-population
  • Underweight individuals in Asian populations have a higher risk of atrial fibrillation (AF).
  • Genetically predicted underweight showed a significant causal relationship with AF (OR: 1.91, 95% CI: 1.51-2.42).
  • Meta-analysis of six cohort studies (427,844 participants) found underweight associated with a 31% greater AF risk (RR: 1.31; 95% CI: 1.13-1.51).
  • Each 1-unit decrease in BMI in underweight individuals was linked to a 6% higher AF risk (95% CI: 1.04-1.09).
  • Further research is needed to confirm if findings apply to non-Asian populations and whether addressing underweight can prevent AF.