Significance of tumor infiltrating granulocytes and neutrophil extracellular traps in colorectal cancer - PubMed
6 hours ago
- #tumor microenvironment
- #neutrophil extracellular traps
- #colorectal cancer
- Higher density of CD66b+ tumor-infiltrating granulocytes is associated with longer colorectal cancer-specific survival.
- Cit-H3+ neutrophil extracellular traps (NETs) correlate with macrophage density and certain serum markers but do not predict patient survival.
- Study analyzed three colorectal cancer cohorts (N=1927) using multiplex immunohistochemistry and machine learning to assess NET and granulocyte densities.