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Real‑life diagnostic and therapeutic approach to CLL/SLL in tuscany: the 2025 consensus - PubMed

3 days ago
  • #Targeted Therapies
  • #Chronic Lymphocytic Leukemia
  • #Diagnostic Approaches
  • The article discusses the real-life diagnostic and therapeutic approaches to Chronic Lymphocytic Leukemia (CLL) and Small Lymphocytic Lymphoma (SLL) in Tuscany, as per the 2025 consensus.
  • Key targeted therapies mentioned include Acalabrutinib, Ibrutinib, Pirtobrutinib, Venetoclax, and Zanubrutinib, focusing on BCL-2 and BTK pathways.
  • References highlight significant studies and updates on CLL epidemiology, pathogenesis, diagnosis, and therapy, including works by Hallek M and others.
  • The article emphasizes the importance of reproducible diagnosis of CLL by flow cytometry, as per European research initiatives.
  • No competing interests were declared by the authors, ensuring unbiased presentation of information.