Potential Synergistic Roles of Ketogenic Diet and Stem Cell Therapy in Parkinson's Disease: A Narrative Review - PubMed
3 hours ago
- #Ketogenic Diet
- #Stem Cell Therapy
- #Parkinson's Disease
- Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's, characterized by dopaminergic signaling loss and abnormal protein aggregates.
- Current treatments like dopamine therapy and deep brain stimulation often fail to control disease progression and cause side effects.
- Stem cell therapy shows promise in reducing neurodegeneration, while dietary modifications like the ketogenic diet may support stem cell renewal.
- Combining ketogenic diet (high-fat, low-carb) with stem cell therapy could address PD's mitochondrial dysfunction, protein clearance defects, and neuroinflammation.
- No clinical trials yet explore the combined efficacy of ketogenic diet and stem cell therapy in PD, necessitating further preclinical and clinical research.