Predictive capacity of peritransplant measurable residual disease thresholds in NPM1-mutant acute myeloid leukemia - PubMed
4 hours ago
- #NPM1
- #AML
- #MRD
- MRD monitoring for NPM1 mutations guides treatment in AML patients.
- Pretransplant MRD negativity predicts favorable long-term survival.
- Post-transplant MRD status at day 30 does not significantly affect survival.
- Derived MRD thresholds effectively stratify high and low-risk patient groups.
- Combined MRD scores pre- and post-HCT improve outcome prediction.
- NPM1-MRD thresholds outperform conventional binary or log-step MRD analysis.