Depression partially mediates the association between frailty and lower urinary tract symptoms in men: cross-sectional analyses of two large population-based studies - PubMed
8 hours ago
- #Depression
- #Lower Urinary Tract Symptoms
- #Frailty
- Study investigates the association between frailty and lower urinary tract symptoms (LUTS) in men using data from NHANES and CHARLS.
- Frailty was measured using the frailty index (FI), and LUTS was defined differently in each study.
- Multivariable logistic regression showed a positive correlation between frailty and LUTS in both US and Chinese men.
- Depression was found to partially mediate the relationship between frailty and LUTS (18.20% in NHANES; 19.63% in CHARLS).
- Subgroup analysis confirmed the influence of covariates on the frailty-LUTS association.
- Higher frailty index correlated with increased risk of LUTS, with depression playing a mediating role.