The Role of Atrial Pacing Support in Cardiac Resynchronization Therapy: A Non-Inferiority Randomized Trial - PubMed
4 hours ago
- #cardiac resynchronization therapy
- #clinical trial
- #atrial pacing
- A two-lead CRT-DX system without atrial pacing is non-inferior to conventional three-lead CRT-D in patients without sinus node dysfunction.
- The primary composite endpoint (all-cause mortality, cardiovascular hospitalization, lead complications) showed no significant difference between groups (HR 0.82, 95% CI 0.54-1.25).
- Fewer atrial lead-related complications occurred with CRT-DX (1.3% vs 4.2%).
- Echocardiographic reverse remodeling and 6-minute walk test distance were similar between groups.
- Only one CRT-DX patient required a standard atrial lead during follow-up.